Interdisciplinary panel offers solutions to improve recruitment for Alzheimer’s clinical trials

Unless cures are found, Alzheimer’s dementia is projected to affect nearly 13 million Americans by 2050—overwhelming families, caregivers and our healthcare system. Yet only one new therapeutic, aducanumab, has come to market in the past 20 years, and therapeutic progress remains hampered for several reasons: recruiting study participants in clinical trials for Alzheimer’s is more […]

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Kinase activity in renal cell carcinoma, benign renal tissue and in response to tyrosine kinase inhibitors

Kinase activity is frequently altered in renal cell carcinoma (RCC), and tyrosine kinase inhibitors (TKIs) are part of the standard treatment strategy in patients with metastatic disease. However, there are still no established biomarkers to predict clinical benefits of a specific TKI. “Despite a number of new treatment options improving RCC patients’ disease control rates […]

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